| Reaction Details |
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 | Report a problem with these data |
| Target | Nucleotide-binding oligomerization domain-containing protein 1 |
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| Ligand | BDBM62238 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis of compounds that inhibit NOD1 revised |
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| IC50 | 20000±n/a nM |
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| Citation |  PubChem, PC SAR analysis of compounds that inhibit NOD1 revised PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Nucleotide-binding oligomerization domain-containing protein 1 |
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| Name: | Nucleotide-binding oligomerization domain-containing protein 1 |
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| Synonyms: | CARD4 | NOD1 | NOD1_HUMAN | nucleotide-binding oligomerization domain containing 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 107699.03 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_5174617 |
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| Residue: | 953 |
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| Sequence: | MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCA
CPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVV
VNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSL
ACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFS
CFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPD
SSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAY
ARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMT
LTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQ
EEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQEL
LRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAK
QKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIY
ETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGV
RELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKIL
DECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHP
SLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKH
LWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF
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| BDBM62238 |
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| n/a |
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| Name | BDBM62238 |
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| Synonyms: | 1-[5-[4-(4-chlorophenyl)piperazin-1-yl]sulfonyl-2,3-dihydroindol-1-yl]propan-1-one | 1-[5-[4-(4-chlorophenyl)piperazino]sulfonylindolin-1-yl]propan-1-one | 1-[5-[[4-(4-chlorophenyl)-1-piperazinyl]sulfonyl]-2,3-dihydroindol-1-yl]-1-propanone | MLS-0412050.0001 | cid_16000292 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24ClN3O3S |
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| Mol. Mass. | 433.952 |
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| SMILES | CCC(=O)N1CCc2cc(ccc12)S(=O)(=O)N1CCN(CC1)c1ccc(Cl)cc1 |
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| Structure | 
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