Reaction Details |
| Report a problem with these data |
Target | Tumor necrosis factor |
---|
Ligand | BDBM62242 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | SAR analysis of inhibitors of TNFa specific NF-kB induction revised |
---|
IC50 | >20000±n/a nM |
---|
Citation | PubChem, PC SAR analysis of inhibitors of TNFa specific NF-kB induction revised PubChem Bioassay(2010)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Tumor necrosis factor |
---|
Name: | Tumor necrosis factor |
Synonyms: | Cachectin | TNF | TNF-a | TNF-alpha | TNFA | TNFA_HUMAN | TNFSF2 | Tumor necrosis factor (TNF-alpha) | Tumor necrosis factor (TNFa) | Tumor necrosis factor alpha (TNFα) | Tumor necrosis factor ligand superfamily member 2 | Tumor necrosis factor, membrane form | Tumor necrosis factor, soluble form | tumor necrosis factor alpha |
Type: | Enzyme |
Mol. Mass.: | 25645.11 |
Organism: | Homo sapiens (Human) |
Description: | P01375 |
Residue: | 233 |
Sequence: | MSTESMIRDVELAEEALPKKTGGPQGSRRCLFLSLFSFLIVAGATTLFCLLHFGVIGPQR
EEFPRDLSLISPLAQAVRSSSRTPSDKPVAHVVANPQAEGQLQWLNRRANALLANGVELR
DNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSYQTKVNLLSAIKSPCQRE
TPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAESGQVYFGIIAL
|
|
|
BDBM62242 |
---|
n/a |
---|
Name | BDBM62242 |
Synonyms: | 4-(piperidinomethyl)-N-p-phenetyl-benzamide | MLS-0412076.0001 | N-(4-ethoxyphenyl)-4-(1-piperidinylmethyl)benzamide | N-(4-ethoxyphenyl)-4-(piperidin-1-ylmethyl)benzamide | cid_41455001 |
Type | Small organic molecule |
Emp. Form. | C21H26N2O2 |
Mol. Mass. | 338.4433 |
SMILES | CCOc1ccc(NC(=O)c2ccc(CN3CCCCC3)cc2)cc1 |
Structure |
|