| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM66118 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase |
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| IC50 | 36414±n/a nM |
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| Citation |  PubChem, PC Epi-absorbance-based dose response assay for common IMP-1 and VIM-2 inhibitors: biochemical high throughput screening assay to identify inhibitors of IMP-1metallo-beta-lactamase PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | Beta-lactamase | metallo-beta-lactamase IMP-1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 27125.88 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | gi_27368096 |
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| Residue: | 246 |
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| Sequence: | MSKLSVFFIFLFCSIATAAESLPDLKIEKLDEGVYVHTSFEEVNGWGVVPKHGLVVLVNA
EAYLIDTPFTAKDTEKLVTWFVERGYKIKGSISSHFHSDSTGGIEWLNSRSIPTYASELT
NELLKKDGKVQATNSFSGVNYWLVKNKIEVFYPGPGHTPDNVVVWLPERKILFGGCFIKP
YGLGNLGDANIEAWPKSAKLLKSKYGKAKLVVPSHSEVGDASLLKLTLEQAVKGLNESKK
PSKPSN
|
|
|
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| BDBM66118 |
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| n/a |
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| Name | BDBM66118 |
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| Synonyms: | (6E)-5-azanylidene-6-[(4-oxidanylidenechromen-3-yl)methylidene]-[1,3]thiazolo[3,2-a]pyrimidin-7-one | (6E)-5-imino-6-[(4-ketochromen-3-yl)methylene]thiazolo[3,2-a]pyrimidin-7-one | (6E)-5-imino-6-[(4-oxo-1-benzopyran-3-yl)methylidene]-7-thiazolo[3,2-a]pyrimidinone | (6E)-5-imino-6-[(4-oxochromen-3-yl)methylidene]-[1,3]thiazolo[3,2-a]pyrimidin-7-one | 5-Imino-6-[1-(4-oxo-4H-chromen-3-yl)-meth-(E)-ylidene]-5,6-dihydro-thiazolo[3,2-a]pyrimidin-7-one | MLS000332035 | SMR000221459 | cid_2037851 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H9N3O3S |
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| Mol. Mass. | 323.326 |
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| SMILES | N=C1N2C=CSC2=NC(=O)\C1=C\c1coc2ccccc2c1=O |c:3,7| |
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| Structure | 
|
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