| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-like protein 11 |
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| Ligand | BDBM63039 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis |
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| EC50 | >350000±n/a nM |
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| Citation |  PubChem, PC Luminescence Cell-Based Dose Retest to Identify Inhibitors of A1 Apoptosis PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Bcl-2-like protein 11 |
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| Name: | Bcl-2-like protein 11 |
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| Synonyms: | B2L11_HUMAN | BCL2-like 11 isoform 1 | BCL2L11 | BIM |
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| Type: | PROTEIN |
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| Mol. Mass.: | 22175.26 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101325 |
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| Residue: | 198 |
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| Sequence: | MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSP
QGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPP
CQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPR
MVILRLLRYIVRLVWRMH
|
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|
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| BDBM63039 |
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| n/a |
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| Name | BDBM63039 |
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| Synonyms: | 2-[6-(4-chlorophenyl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl]sulfanyl-N-(4-methyl-1,3-oxazol-2-yl)acetamide | 2-[6-(4-chlorophenyl)-3-cyano-4-(trifluoromethyl)pyridin-2-yl]sulfanyl-N-(4-methyl-1,3-oxazol-2-yl)ethanamide | 2-[[6-(4-chlorophenyl)-3-cyano-4-(trifluoromethyl)-2-pyridinyl]thio]-N-(4-methyl-2-oxazolyl)acetamide | 2-[[6-(4-chlorophenyl)-3-cyano-4-(trifluoromethyl)-2-pyridyl]thio]-N-(4-methyloxazol-2-yl)acetamide | 2-{[6-(4-chlorophenyl)-3-cyano-4-(trifluoromethyl)-2-pyridinyl]thio}-N-(4-methyl-1,3-oxazol-2-yl)acetamide | MLS000537027 | SMR000143664 | cid_1301870 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H12ClF3N4O2S |
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| Mol. Mass. | 452.837 |
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| SMILES | Cc1coc(NC(=O)CSc2nc(cc(c2C#N)C(F)(F)F)-c2ccc(Cl)cc2)n1 |
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| Structure | 
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