| Reaction Details |
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 | Report a problem with these data |
| Target | Eukaryotic translation initiation factor 4H |
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| Ligand | BDBM61236 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | SAR analysis for the identification of translation initiation inhibitors (eIF4H) |
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| IC50 | 2410±n/a nM |
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| Citation |  PubChem, PC SAR analysis for the identification of translation initiation inhibitors (eIF4H) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Eukaryotic translation initiation factor 4H |
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| Name: | Eukaryotic translation initiation factor 4H |
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| Synonyms: | EIF4H | IF4H_HUMAN | KIAA0038 | WBSCR1 | WSCR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 27385.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15056 |
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| Residue: | 248 |
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| Sequence: | MADFDTYDDRAYSSFGGGRGSRGSAGGHGSRSQKELPTEPPYTAYVGNLPFNTVQGDIDA
IFKDLSIRSVRLVRDKDTDKFKGFCYVEFDEVDSLKEALTYDGALLGDRSLRVDIAEGRK
QDKGGFGFRKGGPDDRGMGSSRESRGGWDSRDDFNSGFRDDFLGGRGGSRPGDRRTGPPM
GSRFRDGPPLRGSNMDFREPTEEERAQRPRLQLKPRTVATPLNQVANPNSAIFGGARPRE
EVVQKEQE
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| BDBM61236 |
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| n/a |
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| Name | BDBM61236 |
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| Synonyms: | 2-{4-[(2-Hydroxy-benzoyl)-hydrazonomethyl]-2-methoxy-phenoxy}-N-phenyl-acetamide | MLS001212428 | N-[[3-methoxy-4-(2-oxidanylidene-2-phenylazanyl-ethoxy)phenyl]methylideneamino]-2-oxidanyl-benzamide | N-[[4-(2-anilino-2-keto-ethoxy)-3-methoxy-benzylidene]amino]-2-hydroxy-benzamide | N-[[4-(2-anilino-2-oxoethoxy)-3-methoxyphenyl]methylideneamino]-2-hydroxybenzamide | SMR000515267 | cid_1105530 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H21N3O5 |
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| Mol. Mass. | 419.4299 |
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| SMILES | COc1cc(C=NNC(=O)c2ccccc2O)ccc1OCC(=O)Nc1ccccc1 |
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| Structure | 
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