| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
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| Ligand | BDBM75763 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay |
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| IC50 | >100000±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase |
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| Name: | Intestinal-type alkaline phosphatase |
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| Synonyms: | ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56804.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1278525 |
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| Residue: | 528 |
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| Sequence: | MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
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| BDBM75763 |
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| n/a |
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| Name | BDBM75763 |
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| Synonyms: | 5-(4-chlorobenzyl)-6,11-diketo-N-(3-morpholinopropyl)benzo[b][1,4]benzothiazepine-3-carboxamide | 5-[(4-chlorophenyl)methyl]-N-(3-morpholin-4-ylpropyl)-6,11-bis(oxidanylidene)benzo[b][1,4]benzothiazepine-3-carboxamide | 5-[(4-chlorophenyl)methyl]-N-(3-morpholin-4-ylpropyl)-6,11-dioxobenzo[b][1,4]benzothiazepine-3-carboxamide | 5-[(4-chlorophenyl)methyl]-N-[3-(4-morpholinyl)propyl]-6,11-dioxo-3-benzo[b][1,4]benzothiazepinecarboxamide | MLS000923978 | SMR000623388 | cid_20860885 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H28ClN3O4S |
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| Mol. Mass. | 538.058 |
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| SMILES | Clc1ccc(CN2c3cc(ccc3S(=O)c3ccccc3C2=O)C(=O)NCCCN2CCOCC2)cc1 |
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| Structure | 
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