| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
|---|
| Ligand | BDBM60597 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of uHTS activators of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase |
|---|
| EC50 | 81500±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of uHTS activators of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Intestinal-type alkaline phosphatase |
|---|
| Name: | Intestinal-type alkaline phosphatase |
|---|
| Synonyms: | ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 56804.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1278525 |
|---|
| Residue: | 528 |
|---|
| Sequence: | MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
|
|
|
|---|
| BDBM60597 |
|---|
| n/a |
|---|
| Name | BDBM60597 |
|---|
| Synonyms: | (E)-N-(1,3-benzothiazol-2-yl)-2-cyano-3-(6-hydroxy-4-keto-chromen-3-yl)acrylamide | (E)-N-(1,3-benzothiazol-2-yl)-2-cyano-3-(6-hydroxy-4-oxo-1-benzopyran-3-yl)-2-propenamide | (E)-N-(1,3-benzothiazol-2-yl)-2-cyano-3-(6-hydroxy-4-oxochromen-3-yl)prop-2-enamide | (E)-N-(1,3-benzothiazol-2-yl)-2-cyano-3-(6-oxidanyl-4-oxidanylidene-chromen-3-yl)prop-2-enamide | (E)-N-Benzothiazol-2-yl-2-cyano-3-(6-hydroxy-4-oxo-4H-chromen-3-yl)-acrylamide | MLS000332015 | SMR000221475 | cid_1839490 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H11N3O4S |
|---|
| Mol. Mass. | 389.384 |
|---|
| SMILES | Oc1ccc2occ(\C=C(/C#N)C(=O)Nc3nc4ccccc4s3)c(=O)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
