| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase 1 |
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| Ligand | BDBM57356 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS activators of Human Intestinal Alkaline Phosphatase using Mouse Intestinal Alkaline Phosphatase |
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| EC50 | 28900±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS activators of Human Intestinal Alkaline Phosphatase using Mouse Intestinal Alkaline Phosphatase PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase 1 |
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| Name: | Intestinal-type alkaline phosphatase 1 |
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| Synonyms: | Alpi | PPBI1_RAT |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 58396.39 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P15693 |
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| Residue: | 540 |
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| Sequence: | MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFL
GDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYL
CGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTY
AHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGD
SDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNR
NASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEK
ASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYV
LNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAH
VMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS
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| BDBM57356 |
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| n/a |
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| Name | BDBM57356 |
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| Synonyms: | 2-[1-(1H-benzimidazol-2-yl)-3-(3-methylphenyl)propan-2-yl]-1H-benzimidazole | 2-[1-(1H-benzimidazol-2-ylmethyl)-2-(m-tolyl)ethyl]-1H-benzimidazole | MLS000557705 | SMR000174752 | cid_2837680 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H22N4 |
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| Mol. Mass. | 366.4583 |
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| SMILES | Cc1cccc(CC(Cc2nc3ccccc3[nH]2)c2nc3ccccc3[nH]2)c1 |
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| Structure | 
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