| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-3 |
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| Ligand | BDBM76363 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay |
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| IC50 | 34300±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of inhibitors of Sentrin-specific proteases (SENPs) using a Caspase-3 Selectivity assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Caspase-3 |
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| Name: | Caspase-3 |
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| Synonyms: | Apopain | CASP-3 | CASP3 | CASP3_HUMAN | CPP-32 | CPP32 | Caspase 3 | Caspase-3 subunit p12 | Caspase-3 subunit p17 | Cysteine protease CPP32 | SCA-1 | SREBP cleavage activity 1 | Yama protein | caspase-3 preproprotein |
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| Type: | Hydrolase; heterotetramer of two heterodimers |
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| Mol. Mass.: | 31607.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 277 |
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| Sequence: | MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG
MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS
HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD
DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN
RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
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|
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| BDBM76363 |
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| n/a |
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| Name | BDBM76363 |
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| Synonyms: | 4-(4-fluorophenyl)-N-phenyl-3,6-dihydro-1(2H)-pyridinecarboxamide | 4-(4-fluorophenyl)-N-phenyl-3,6-dihydro-2H-pyridine-1-carboxamide | MLS000100266 | SMR000082286 | cid_2980777 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17FN2O |
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| Mol. Mass. | 296.3388 |
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| SMILES | Fc1ccc(cc1)C1=CCN(CC1)C(=O)Nc1ccccc1 |t:8| |
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| Structure | 
|
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