BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSentrin-specific protease 8
LigandBDBM76453
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay
IC50 15400±n/a nM
Citation PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Sentrin-specific protease 8
Name:Sentrin-specific protease 8
Synonyms:DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8
Type:Enzyme Catalytic Domain
Mol. Mass.:24104.52
Organism:Homo sapiens (Human)
Description:gi_262118306
Residue:212
Sequence:
MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM76453
n/a
NameBDBM76453
Synonyms:(1-chloranylnaphthalen-2-yl) azepane-1-carboxylate | (1-chloronaphthalen-2-yl) azepane-1-carboxylate | 1-azepanecarboxylic acid (1-chloro-2-naphthalenyl) ester | 1-chloro-2-naphthyl 1-azepanecarboxylate | MLS000582937 | SMR000201646 | azepane-1-carboxylic acid (1-chloro-2-naphthyl) ester | cid_2983964
TypeSmall organic molecule
Emp. Form.C17H18ClNO2
Mol. Mass.303.783
SMILESClc1c(OC(=O)N2CCCCCC2)ccc2ccccc12
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: