| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 8 |
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| Ligand | BDBM76722 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay |
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| IC50 | 3400±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sentrin-specific protease 8 |
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| Name: | Sentrin-specific protease 8 |
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| Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 24104.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_262118306 |
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| Residue: | 212 |
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| Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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| BDBM76722 |
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| n/a |
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| Name | BDBM76722 |
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| Synonyms: | 2-(3H-benzimidazole-5-carbonylamino)-4-methyl-thiazole-5-carboxylic acid ethyl ester | 2-[[3H-benzimidazol-5-yl(oxo)methyl]amino]-4-methyl-5-thiazolecarboxylic acid ethyl ester | MLS001173978 | SMR000595705 | cid_9110686 | ethyl 2-(3H-benzimidazol-5-ylcarbonylamino)-4-methyl-1,3-thiazole-5-carboxylate | ethyl 2-(3H-benzimidazole-5-carbonylamino)-4-methyl-1,3-thiazole-5-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C15H14N4O3S |
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| Mol. Mass. | 330.362 |
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| SMILES | CCOC(=O)c1sc(NC(=O)c2ccc3nc[nH]c3c2)nc1C |
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| Structure | 
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