Reaction Details |
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Target | Mitochondrial import inner membrane translocase subunit TIM10 |
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Ligand | BDBM78181 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay |
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IC50 | 6400±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Mitochondrial import inner membrane translocase subunit TIM10 |
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Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 10303.50 |
Organism: | Saccharomyces cerevisiae S288c |
Description: | gi_285809906 |
Residue: | 93 |
Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
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BDBM78181 |
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n/a |
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Name | BDBM78181 |
Synonyms: | (E)-3-(3-Benzotriazol-1-ylmethyl-4-methoxy-phenyl)-1-phenyl-propenone | (E)-3-[3-(1-benzotriazolylmethyl)-4-methoxyphenyl]-1-phenyl-2-propen-1-one | (E)-3-[3-(benzotriazol-1-ylmethyl)-4-methoxy-phenyl]-1-phenyl-prop-2-en-1-one | (E)-3-[3-(benzotriazol-1-ylmethyl)-4-methoxyphenyl]-1-phenylprop-2-en-1-one | MLS000589828 | SMR000217110 | cid_6184004 |
Type | Small organic molecule |
Emp. Form. | C23H19N3O2 |
Mol. Mass. | 369.4159 |
SMILES | COc1ccc(\C=C\C(=O)c2ccccc2)cc1Cn1nnc2ccccc12 |
Structure |
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