Reaction Details |
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Target | Ubiquitin-conjugating enzyme E2 N |
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Ligand | BDBM43873 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay |
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IC50 | >20000±0 nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Ubiquitin-conjugating enzyme E2 N |
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Name: | Ubiquitin-conjugating enzyme E2 N |
Synonyms: | BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N |
Type: | PROTEIN |
Mol. Mass.: | 17137.61 |
Organism: | Homo sapiens (Human) |
Description: | EBI_101440 |
Residue: | 152 |
Sequence: | MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
EYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDP
LANDVAEQWKTNEAQAIETARAWTRLYAMNNI
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BDBM43873 |
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n/a |
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Name | BDBM43873 |
Synonyms: | 1-[(Z)-[1-[(4-fluorophenyl)methyl]-2-oxidanylidene-indol-3-ylidene]amino]thiourea | MLS000587573 | SMR000211591 | [(Z)-[1-(4-fluorobenzyl)-2-keto-indolin-3-ylidene]amino]thiourea | [(Z)-[1-[(4-fluorophenyl)methyl]-2-oxo-3-indolylidene]amino]thiourea | [(Z)-[1-[(4-fluorophenyl)methyl]-2-oxoindol-3-ylidene]amino]thiourea | cid_6870780 |
Type | Small organic molecule |
Emp. Form. | C16H13FN4OS |
Mol. Mass. | 328.364 |
SMILES | NC(=S)NN=C1C(=O)N(Cc2ccc(F)cc2)c2ccccc12 |w:4.3| |
Structure |
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