| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ubiquitin-conjugating enzyme E2 N |
|---|
| Ligand | BDBM43211 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm |
|---|
| IC50 | 15860±973 nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Ubiquitin-conjugating enzyme E2 N |
|---|
| Name: | Ubiquitin-conjugating enzyme E2 N |
|---|
| Synonyms: | BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 17137.61 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | EBI_101440 |
|---|
| Residue: | 152 |
|---|
| Sequence: | MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
EYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDP
LANDVAEQWKTNEAQAIETARAWTRLYAMNNI
|
|
|
|---|
| BDBM43211 |
|---|
| n/a |
|---|
| Name | BDBM43211 |
|---|
| Synonyms: | 6-(4-Methoxy-phenyl)-2-piperazin-1-yl-pyrimidine-4-carbonitrile | 6-(4-methoxyphenyl)-2-(1-piperazinyl)-4-pyrimidinecarbonitrile | 6-(4-methoxyphenyl)-2-piperazin-1-yl-pyrimidine-4-carbonitrile | 6-(4-methoxyphenyl)-2-piperazin-1-ylpyrimidine-4-carbonitrile | 6-(4-methoxyphenyl)-2-piperazino-pyrimidine-4-carbonitrile | MLS000557435 | SMR000148351 | cid_943399 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H17N5O |
|---|
| Mol. Mass. | 295.3391 |
|---|
| SMILES | COc1ccc(cc1)-c1cc(nc(n1)N1CCNCC1)C#N |
|---|
| Structure | 
|
|---|
Search and Browse
