Reaction Details |
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Target | Mitochondrial import inner membrane translocase subunit TIM10 |
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Ligand | BDBM77861 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. |
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IC50 | >100000±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Mitochondrial import inner membrane translocase subunit TIM10 |
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Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 10303.50 |
Organism: | Saccharomyces cerevisiae S288c |
Description: | gi_285809906 |
Residue: | 93 |
Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
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BDBM77861 |
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n/a |
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Name | BDBM77861 |
Synonyms: | 2-(5-Phenyl-2,3-dihydro-[1,3,4]thiadiazol-2-yl)-phenol | 2-(5-phenyl-2,3-dihydro-1,3,4-thiadiazol-2-yl)phenol | MLS001212798 | SMR000517222 | cid_2860190 |
Type | Small organic molecule |
Emp. Form. | C14H12N2OS |
Mol. Mass. | 256.323 |
SMILES | Oc1ccccc1C1=NNC(S1)c1ccccc1 |t:8| |
Structure |
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