| Reaction Details |
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 | Report a problem with these data |
| Target | BRCA1-associated RING domain protein 1 |
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| Ligand | BDBM79634 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of Inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay |
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| IC50 | 6640±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of Inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| BRCA1-associated RING domain protein 1 |
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| Name: | BRCA1-associated RING domain protein 1 |
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| Synonyms: | BARD-1 | BARD1 | BARD1_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 86678.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_116241265 |
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| Residue: | 777 |
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| Sequence: | MPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREP
VCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNEL
SDLKEDKPRKSLFNDAGNKKNSIKMWFSPRSKKVRYVVSKASVQTQPAIKKDASAQQDSY
EFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEKEDGEFDSKEESKQKLV
SFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTP
EKVCKNYLTSKKSLPLENNGKRGHHNRLSSPISKRCRTSILSTSGDFVKQTVPSENIPLP
ECSSPPSCKRKVGGTSGRKNSNMSDEFISLSPGTPPSTLSSSSYRRVMSSPSAMKLLPNM
AVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELL
LQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMK
SLLLLPEKNESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEF
DSTVTHVVVPGDAVQSTLKCMLGILNGCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRS
RLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTV
AYHARPDSDQRFCTQYIIYEDLCNYHPERVRQGKVWKAPSSWFIDCVMSFELLPLDS
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| BDBM79634 |
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| n/a |
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| Name | BDBM79634 |
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| Synonyms: | (E)-3-(2-Chloro-6-fluoro-phenyl)-1-(4-hydroxy-phenyl)-propenone | (E)-3-(2-chloranyl-6-fluoranyl-phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one | (E)-3-(2-chloro-6-fluoro-phenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one | (E)-3-(2-chloro-6-fluorophenyl)-1-(4-hydroxyphenyl)-2-propen-1-one | (E)-3-(2-chloro-6-fluorophenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one | MLS000778288 | SMR000415082 | cid_5921223 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10ClFO2 |
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| Mol. Mass. | 276.69 |
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| SMILES | Oc1ccc(cc1)C(=O)\C=C\c1c(F)cccc1Cl |
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| Structure | 
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