| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
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| Ligand | BDBM80164 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen |
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| Temperature | 298.15±n/a K |
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| IC50 | >100000±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| DNA dC->dU-editing enzyme APOBEC-3A |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
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| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23013.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21955158 |
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| Residue: | 199 |
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| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
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| BDBM80164 |
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| n/a |
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| Name | BDBM80164 |
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| Synonyms: | 3-(1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-4-(veratrylideneamino)-1H-1,2,4-triazole-5-thione | 4-[(3,4-dimethoxyphenyl)methylideneamino]-3-(1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-1H-1,2,4-triazole-5-thione | 4-{[1-(3,4-Dimethoxy-phenyl)-meth-(E)-ylidene]-amino}-5-(1,4,5,6-tetrahydro-cyclopentapyrazol-3-yl)-4H-[1,2,4]triazole-3-thiol | MLS000331448 | SMR000220875 | cid_1423282 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18N6O2S |
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| Mol. Mass. | 370.429 |
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| SMILES | COc1ccc(C=Nn2c(n[nH]c2=S)-c2n[nH]c3CCCc23)cc1OC |w:7.7| |
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| Structure | 
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