BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetC-C chemokine receptor type 6
LigandBDBM48771
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay
IC50 23500±n/a nM
Citation PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
C-C chemokine receptor type 6
Name:C-C chemokine receptor type 6
Synonyms:C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22
Type:Enzyme
Mol. Mass.:42510.84
Organism:Homo sapiens (Human)
Description:P51684
Residue:374
Sequence:
MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
SETADNDNASSFTM
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM48771
n/a
NameBDBM48771
Synonyms:(Z)-2-butenedioic acid;2-[[2-(methylaminomethyl)phenyl]thio]benzene-1,4-diol | (Z)-but-2-enedioic acid;2-[2-(methylaminomethyl)phenyl]sulfanylbenzene-1,4-diol | 2-({2-[(methylamino)methyl]phenyl}sulfanyl)-1,4-benzenediol | MLS000704381 | SMR000230499 | cid_15945829 | maleic acid;2-[[2-(methylaminomethyl)phenyl]thio]hydroquinone
TypeSmall organic molecule
Emp. Form.C14H15NO2S
Mol. Mass.261.339
SMILESCNCc1ccccc1Sc1cc(O)ccc1O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: