| Reaction Details |
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 | Report a problem with these data |
| Target | Hrh3 protein |
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| Ligand | BDBM22893 |
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| Substrate/Competitor | n/a |
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| Ki | >10000±n/a nM |
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| Comments | PDSP_1588 |
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| Citation |  West, RE; Zweig, A; Granzow, RT; Siegel, MI; Egan, RW Biexponential kinetics of (R)-alpha-[3H]methylhistamine binding to the rat brain H3 histamine receptor. J Neurochem55:1612-6 (1990) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Hrh3 protein |
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| Name: | Hrh3 protein |
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| Synonyms: | HISTAMINE H3 | HRH3 | Hrh3 protein |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37860.96 |
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| Organism: | RAT |
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| Description: | Q5PPG3 |
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| Residue: | 344 |
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| Sequence: | MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFV
ADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCAS
SVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGG
SSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAG
PEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRGSKPSASSASLEKRMKMVSQSITQRF
RLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDY
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| BDBM22893 |
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| n/a |
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| Name | BDBM22893 |
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| Synonyms: | CHEMBL512 | Ranitidine | ZANTAC | dimethyl[(5-{[(2-{[(E)-1-(methylamino)-2-nitroethenyl]amino}ethyl)sulfanyl]methyl}furan-2-yl)methyl]amine |
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| Type | Small organic molecule |
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| Emp. Form. | C13H22N4O3S |
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| Mol. Mass. | 314.404 |
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| SMILES | CN\C([CH-][N+]([O-])=O)=[NH+]/CCSCc1ccc(CN(C)C)o1 |
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| Structure | 
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