| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate receptor ionotropic, kainate 4 |
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| Ligand | BDBM50252103 |
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| Substrate/Competitor | n/a |
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| Ki | 10.5±n/a nM |
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| Comments | PDSP_725 |
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| Citation |  Kamboj, RK; Schoepp, DD; Nutt, S; Shekter, L; Korczak, B; True, RA; Rampersad, V; Zimmerman, DM; Wosnick, MA Molecular cloning, expression, and pharmacological characterization of humEAA1, a human kainate receptor subunit. J Neurochem62:1-9 (1994) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Glutamate receptor ionotropic, kainate 4 |
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| Name: | Glutamate receptor ionotropic, kainate 4 |
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| Synonyms: | GRIK | GRIK4 | GRIK4 protein | GRIK4_HUMAN | Glutamate-Kainate EAA1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 107246.86 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q16099 |
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| Residue: | 956 |
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| Sequence: | MPRVSAPLVLLPAWLVMVACSPHSLRIAAILDDPMECSRGERLSITLAKNRINRAPERLG
KAKVEVDIFELLRDSEYETAETMCQILPKGVVAVLGPSSSPASSSIISNICGEKEVPHFK
VAPEEFVKFQFQRFTTLNLHPSNTDISVAVAGILNFFNCTTACLICAKAECLLNLEKLLR
QFLISKDTLSVRMLDDTRDPTPLLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAY
YTYIFTNLEFSLQRMDSLVDDRVNILGFSIFNQSHAFFQEFAQSLNQSWQENCDHVPFTG
PALSSALLFDAVYAVVTAVQELNRSQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLT
GHIEFNSKGQRSNYALKILQFTRNGFRQIGQWHVAEGLSMDSHLYASNISDTLFNTTLVV
TTILENPYLMLKGNHQEMEGNDRYEGFCVDMLKELAEILRFNYKIRLVGDGVYGVPEANG
TWTGMVGELIARKADLAVAGLTITAEREKVIDFSKPFMTLGISILYRVHMGRKPGYFSFL
DPFSPGVWLFMLLAYLAVSCVLFLVARLTPYEWYSPHPCAQGRCNLLVNQYSLGNSLWFP
VGGFMQQGSTIAPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMDVPIESVDDLA
DQTAIEYGTIHGGSSMTFFQNSRYQTYQRMWNYMYSKQPSVFVKSTEEGIARVLNSNYAF
LLESTMNEYYRQRNCNLTQIGGLLDTKGYGIGMPVGSVFRDEFDLAILQLQENNRLEILK
RKWWEGGKCPKEEDHRAKGLGMENIGGIFVVLICGLIVAIFMAMLEFLWTLRHSEATEVS
VCQEMVTELRSIILCQDSIHPRRRRAAVPPPRPPIPEERRPRGTATLSNGKLCGAGEPDQ
LAQRLAQEAALVARGCTHIRVCPECRRFQGLRARPSPARSEESLEWEKTTNSSEPE
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| BDBM50252103 |
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| n/a |
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| Name | BDBM50252103 |
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| Synonyms: | (2S,3S,4S)-2-CARBOXY-4-[(1Z,3E,5R)-5-CARBOXY-1-METHYL-1,3-HEXADIENYL]-3-PYRROLIDINEACETIC ACID | CHEMBL482097 | domoic acid | domoric acid |
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| Type | Small organic molecule |
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| Emp. Form. | C15H21NO6 |
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| Mol. Mass. | 311.3303 |
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| SMILES | C[C@H](\C=C\C=C(/C)[C@H]1CN[C@@H]([C@H]1CC(O)=O)C(O)=O)C(O)=O |r| |
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| Structure | 
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