| Reaction Details |
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 | Report a problem with these data |
| Target | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
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| Ligand | BDBM50392 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay |
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| IC50 | 4852±212 nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits for Scp-1 phosphatase using a colorimetric assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
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| Name: | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 |
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| Synonyms: | CTDS1_HUMAN | CTDSP1 | NIF3 | NLIIF | SCP1 | carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 29199.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_10864009 |
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| Residue: | 261 |
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| Sequence: | MDSSAVITQISKEEARGPLRGKGDQKSAASQKPRSRGILHSLFCCVCRDDGEALPAHSGA
PLLVEENGAIPKQTPVQYLLPEAKAQDSDKICVVIDLDETLVHSSFKPVNNADFIIPVEI
DGVVHQVYVLKRPHVDEFLQRMGELFECVLFTASLAKYADPVADLLDKWGAFRARLFRES
CVFHRGNYVKDLSRLGRDLRRVLILDNSPASYVFHPDNAVPVASWFDNMSDTELHDLLPF
FEQLSRVDDVYSVLRQPRPGS
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| BDBM50392 |
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| n/a |
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| Name | BDBM50392 |
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| Synonyms: | (E)-3-(3,4-dimethoxyphenyl)-N-[(2-hydroxy-5-nitro-phenyl)thiocarbamoyl]acrylamide | (E)-3-(3,4-dimethoxyphenyl)-N-[(2-hydroxy-5-nitroanilino)-sulfanylidenemethyl]-2-propenamide | (E)-3-(3,4-dimethoxyphenyl)-N-[(2-hydroxy-5-nitrophenyl)carbamothioyl]prop-2-enamide | (E)-3-(3,4-dimethoxyphenyl)-N-[(5-nitro-2-oxidanyl-phenyl)carbamothioyl]prop-2-enamide | MLS000714183 | SMR000274163 | cid_5768784 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17N3O6S |
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| Mol. Mass. | 403.409 |
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| SMILES | COc1ccc(C=CC(=O)NC(=S)Nc2cc(ccc2O)[N+]([O-])=O)cc1OC |w:6.5| |
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| Structure | 
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