Reaction Details |
| Report a problem with these data |
Target | Endoribonuclease toxin MazF |
---|
Ligand | BDBM66133 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay |
---|
EC50 | >99000±n/a nM |
---|
Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay PubChem Bioassay(2011)[AID] |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Endoribonuclease toxin MazF |
---|
Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
|
|
|
BDBM66133 |
---|
n/a |
---|
Name | BDBM66133 |
Synonyms: | (1,1-diketo-1,2-benzothiazol-3-yl)-[[4-(dimethylamino)benzylidene]amino]-methyl-amine | 4-(dimethylamino)benzaldehyde (1,1-dioxido-1,2-benzisothiazol-3-yl)(methyl)hydrazone | MLS001196384 | N-[[4-(dimethylamino)phenyl]methylideneamino]-N-methyl-1,1-bis(oxidanylidene)-1,2-benzothiazol-3-amine | N-[[4-(dimethylamino)phenyl]methylideneamino]-N-methyl-1,1-dioxo-1,2-benzothiazol-3-amine | SMR000556209 | cid_5236773 |
Type | Small organic molecule |
Emp. Form. | C17H18N4O2S |
Mol. Mass. | 342.415 |
SMILES | CN(C)c1ccc(C=NN(C)C2=NS(=O)(=O)c3ccccc23)cc1 |t:11| |
Structure |
|