Reaction Details |
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Target | Endoribonuclease toxin MazF |
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Ligand | BDBM32010 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen |
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EC50 | 56600±n/a nM |
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Citation | PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Assay Method |
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Endoribonuclease toxin MazF |
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Name: | Endoribonuclease toxin MazF |
Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 12100.43 |
Organism: | Escherichia coli str. K-12 substr. MG1655 |
Description: | gi_16130689 |
Residue: | 111 |
Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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BDBM32010 |
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n/a |
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Name | BDBM32010 |
Synonyms: | (4Z)-4-[[4-(dimethylamino)anilino]methylene]-2-phenyl-2-oxazolin-5-one | (4Z)-4-[[4-(dimethylamino)anilino]methylidene]-2-phenyl-1,3-oxazol-5-one | (4Z)-4-[[4-(dimethylamino)anilino]methylidene]-2-phenyl-5-oxazolone | (4Z)-4-[[[4-(dimethylamino)phenyl]amino]methylidene]-2-phenyl-1,3-oxazol-5-one | 4-[1-(4-Dimethylamino-phenylamino)-meth-(Z)-ylidene]-2-phenyl-4H-oxazol-5-one | MLS000077184 | SMR000009577 | cid_5378674 |
Type | Small organic molecule |
Emp. Form. | C18H17N3O2 |
Mol. Mass. | 307.3465 |
SMILES | CN(C)c1ccc(cc1)N=Cc1nc(oc1O)-c1ccccc1 |w:9.9| |
Structure |
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