| Reaction Details |
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 | Report a problem with these data |
| Target | Endoribonuclease toxin MazF |
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| Ligand | BDBM43814 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen |
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| EC50 | 69500±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation uHTS hits for MazEF TA System activators via a fluorescence-based single-stranded RNase assay counterscreen PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Endoribonuclease toxin MazF |
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| Name: | Endoribonuclease toxin MazF |
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| Synonyms: | MAZF_ECOLI | chpA | chpAK | mRNA interferase toxin, antitoxin is MazE | mazF |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 12100.43 |
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| Organism: | Escherichia coli str. K-12 substr. MG1655 |
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| Description: | gi_16130689 |
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| Residue: | 111 |
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| Sequence: | MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTGMCLCVPCTTQSKGYPF
EVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLIKAKINVLIG
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| BDBM43814 |
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| n/a |
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| Name | BDBM43814 |
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| Synonyms: | (3Z)-1-butyl-3-[(2-hydroxyphenyl)hydrazinylidene]-2-indolone | (3Z)-1-butyl-3-[(2-hydroxyphenyl)hydrazinylidene]indol-2-one | (3Z)-1-butyl-3-[(2-hydroxyphenyl)hydrazono]oxindole | MLS-0106435.0001 | cid_25199560 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19N3O2 |
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| Mol. Mass. | 309.3624 |
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| SMILES | CCCCN1C(=O)C(=NNc2ccccc2O)c2ccccc12 |w:8.8| |
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| Structure | 
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