| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-3 |
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| Ligand | BDBM50240930 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1669327 (CHEMBL4019215) |
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| IC50 | >200000±n/a nM |
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| Citation |  Qi, Q; Obianyo, O; Du, Y; Fu, H; Li, S; Ye, K Blockade of Asparagine Endopeptidase Inhibits Cancer Metastasis. J Med Chem60:7244-7255 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Caspase-3 |
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| Name: | Caspase-3 |
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| Synonyms: | Apopain | CASP-3 | CASP3 | CASP3_HUMAN | CPP-32 | CPP32 | Caspase 3 | Caspase-3 subunit p12 | Caspase-3 subunit p17 | Cysteine protease CPP32 | SCA-1 | SREBP cleavage activity 1 | Yama protein | caspase-3 preproprotein |
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| Type: | Hydrolase; heterotetramer of two heterodimers |
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| Mol. Mass.: | 31607.55 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 277 |
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| Sequence: | MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG
MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS
HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD
DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN
RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH
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| BDBM50240930 |
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| n/a |
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| Name | BDBM50240930 |
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| Synonyms: | CHEMBL4093898 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H12N4O2S |
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| Mol. Mass. | 240.282 |
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| SMILES | CCn1c(=O)n(C)c2nc(S)n(C)c2c1=O |
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| Structure | 
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