| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Interleukin-6 |
|---|
| Ligand | BDBM50252380 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1684684 |
|---|
| IC50 | 18900±n/a nM |
|---|
| Citation |  Kim, D; Won, HY; Hwang, ES; Kim, YK; Choo, HP Synthesis of benzoxazole derivatives as interleukin-6 antagonists. Bioorg Med Chem25:3127-3134 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Interleukin-6 |
|---|
| Name: | Interleukin-6 |
|---|
| Synonyms: | B-cell stimulatory factor 2 | BSF-2 | CDF | CTL differentiation factor | Hybridoma growth factor | IFN-beta-2 | IFNB2 | IL-6 | IL6 | IL6_HUMAN | Interferon beta-2 |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 23717.96 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P05231 |
|---|
| Residue: | 212 |
|---|
| Sequence: | MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYI
LDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLL
EFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQ
AQNQWLQDMTTHLILRSFKEFLQSSLRALRQM
|
|
|
|---|
| BDBM50252380 |
|---|
| n/a |
|---|
| Name | BDBM50252380 |
|---|
| Synonyms: | CHEMBL4068283 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H15N3O |
|---|
| Mol. Mass. | 253.2991 |
|---|
| SMILES | CCc1ccc(Nc2nc3cc(N)ccc3o2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
