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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Adenosine receptor A1 | ||
| Ligand | BDBM50007843 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_27567 | ||
| Ki | 160±n/a nM | ||
| Citation |  Katsushima, T; Nieves, L; Wells, JN Structure-activity relationships of 8-cycloalkyl-1,3-dipropylxanthines as antagonists of adenosine receptors. J Med Chem33:1906-10 (1990) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Adenosine receptor A1 | |||
| Name: | Adenosine receptor A1 | ||
| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 36520.92 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P30542 | ||
| Residue: | 326 | ||
| Sequence: |
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| BDBM50007843 | |||
| n/a | |||
| Name | BDBM50007843 | ||
| Synonyms: | 8-(4-Amino-cyclohexyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione (CF3CO2H) | 8-(4-Amino-cyclohexyl)-1,3-dipropyl-3,7-dihydro-purine-2,6-dione (HCl.1/2H2O) | CHEMBL58879 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H27N5O2 | ||
| Mol. Mass. | 333.4286 | ||
| SMILES | CCCn1c2nc([nH]c2c(=O)n(CCC)c1=O)C1CCC(N)CC1 |(1.85,-15.93,;1.85,-14.38,;3.18,-13.61,;3.18,-12.05,;4.53,-11.28,;6.01,-11.76,;6.92,-10.5,;6.01,-9.23,;4.53,-9.72,;3.18,-8.93,;3.18,-7.37,;1.84,-9.72,;.48,-8.93,;.48,-7.37,;-.88,-6.58,;1.84,-11.28,;.46,-12.08,;8.32,-10.5,;9.02,-9.29,;10.42,-9.29,;11.13,-10.5,;12.53,-10.5,;10.42,-11.71,;9.02,-11.71,)| | ||
| Structure | 
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