| Reaction Details |
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 | Report a problem with these data |
| Target | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 |
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| Ligand | BDBM50266937 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1701592 (CHEMBL4052574) |
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| IC50 | 20±n/a nM |
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| Citation |  Lanier, M; Cole, DC; Istratiy, Y; Klein, MG; Schwartz, PA; Tjhen, R; Jennings, A; Hixon, MS Repurposing Suzuki Coupling Reagents as a Directed Fragment Library Targeting Serine Hydrolases and Related Enzymes. J Med Chem60:5209-5215 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 |
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| Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 |
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| Synonyms: | Autotaxin | Autotaxin (mATX) | ENPP2_MOUSE | Ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2) | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | Enpp2 | Npps2 | Pdnp2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 98896.47 |
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| Organism: | Mus musculus |
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| Description: | n/a |
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| Residue: | 862 |
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| Sequence: | MARQGCFGSYQVISLFTFAIGVNLCLGFTASRIKRAEWDEGPPTVLSDSPWTNTSGSCKG
RCFELQEVGPPDCRCDNLCKSYSSCCHDFDELCLKTARGWECTKDRCGEVRNEENACHCS
EDCLSRGDCCTNYQVVCKGESHWVDDDCEEIRVPECPAGFVRPPLIIFSVDGFRASYMKK
GSKVMPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPVFDAT
FHLRGREKFNHRWWGGQPLWITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERP
SVYAFYSEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHG
MEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRPKIPNNLKYDPKAIIANLTCKKPDQHF
KPYMKQHLPKRLHYANNRRIEDLHLLVERRWHVARKPLDVYKKPSGKCFFQGDHGFDNKV
NSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPAPNNGTHGSLNHLLRTNTFR
PTLPEEVSRPNYPGIMYLQSDFDLGCTCDDKVEPKNKLEELNKRLHTKGSTEERHLLYGR
PAVLYRTSYDILYHTDFESGYSEIFLMPLWTSYTISKQAEVSSIPEHLTNCVRPDVRVSP
GFSQNCLAYKNDKQMSYGFLFPPYLSSSPEAKYDAFLVTNMVPMYPAFKRVWTYFQRVLV
KKYASERNGVNVISGPIFDYNYNGLRDIEDEIKQYVEGSSIPVPTHYYSIITSCLDFTQP
ADKCDGPLSVSSFILPHRPDNDESCNSSEDESKWVEELMKMHTARVRDIEHLTGLDFYRK
TSRSYSEILTLKTYLHTYESEI
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| BDBM50266937 |
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| n/a |
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| Name | BDBM50266937 |
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| Synonyms: | CHEMBL4095125 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H27BCl2N2O3S |
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| Mol. Mass. | 505.265 |
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| SMILES | OB(O)c1ccc(CCCN2CCC(CC2)c2nc(O)c(Cc3ccc(Cl)c(Cl)c3)s2)cc1 |
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| Structure | 
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