| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50266973 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1701703 (CHEMBL4052936) |
|---|
| Ki | 202±n/a nM |
|---|
| Citation |  Michino, M; Boateng, CA; Donthamsetti, P; Yano, H; Bakare, OM; Bonifazi, A; Ellenberger, MP; Keck, TM; Kumar, V; Zhu, C; Verma, R; Deschamps, JR; Javitch, JA; Newman, AH; Shi, L Toward Understanding the Structural Basis of Partial Agonism at the Dopamine D J Med Chem60:580-593 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
|---|
| Type: | Cell-surface receptors |
|---|
| Mol. Mass.: | 50647.10 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P14416 |
|---|
| Residue: | 443 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
|
|
|
|---|
| BDBM50266973 |
|---|
| n/a |
|---|
| Name | BDBM50266973 |
|---|
| Synonyms: | CHEMBL4081424 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H26Cl2N4O2 |
|---|
| Mol. Mass. | 473.395 |
|---|
| SMILES | O[C@H](CCNC(=O)c1cnc2ccccc2c1)CN1CCN(CC1)c1cccc(Cl)c1Cl |r| |
|---|
| Structure | 
|
|---|
Search and Browse
