| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50269638 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1706998 (CHEMBL4058231) |
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| Ki | 7.3±n/a nM |
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| Citation |  Pasquinucci, L; Turnaturi, R; Prezzavento, O; Arena, E; Aricò, G; Georgoussi, Z; Parenti, R; Cantarella, G; Parenti, C Development of novel LP1-based analogues with enhanced delta opioid receptor profile. Bioorg Med Chem25:4745-4752 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42744.99 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | P41144 |
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| Residue: | 380 |
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| Sequence: | MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRV
RNTVQDPAYMRNVDGVNKPV
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| BDBM50269638 |
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| n/a |
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| Name | BDBM50269638 |
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| Synonyms: | CHEMBL4066846 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27NO2 |
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| Mol. Mass. | 337.4553 |
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| SMILES | [H][C@]12Cc3ccc(O)cc3[C@](C)(CCN1C[C@H](O)c1ccccc1)[C@H]2C |r,THB:8:9:24:14.12.13,15:14:24:9.3.2| |
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| Structure | 
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