| Reaction Details |
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 | Report a problem with these data |
| Target | Pancreatic alpha-amylase |
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| Ligand | BDBM50274062 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1713756 (CHEMBL4123805) |
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| IC50 | 32270±n/a nM |
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| Citation |  Prabha, B; Neethu, S; Krishnan, SL; Sherin, DR; Madhukrishnan, M; Ananthakrishnan, R; Rameshkumar, KB; Manojkumar, TK; Jayamurthy, P; Radhakrishnan, KV Antidiabetic potential of phytochemicals isolated from the stem bark of Myristica fatua Houtt. var. magnifica (Bedd.) Sinclair. Bioorg Med Chem26:3461-3467 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Pancreatic alpha-amylase |
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| Name: | Pancreatic alpha-amylase |
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| Synonyms: | 1,4-alpha-D-glucan glucanohydrolase | AMY2 | AMYP_PIG | Pancreatic α-amylase | Pancreatic α-amylase |
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| Type: | Protein |
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| Mol. Mass.: | 57088.07 |
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| Organism: | Sus scrofa (Pig) |
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| Description: | P00690 |
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| Residue: | 511 |
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| Sequence: | MKLFLLLSAFGFCWAQYAPQTQSGRTSIVHLFEWRWVDIALECERYLGPKGFGGVQVSPP
NENIVVTNPSRPWWERYQPVSYKLCTRSGNENEFRDMVTRCNNVGVRIYVDAVINHMCGS
GAAAGTGTTCGSYCNPGNREFPAVPYSAWDFNDGKCKTASGGIESYNDPYQVRDCQLVGL
LDLALEKDYVRSMIADYLNKLIDIGVAGFRIDASKHMWPGDIKAVLDKLHNLNTNWFPAG
SRPFIFQEVIDLGGEAIQSSEYFGNGRVTEFKYGAKLGTVVRKWSGEKMSYLKNWGEGWG
FMPSDRALVFVDNHDNQRGHGAGGASILTFWDARLYKVAVGFMLAHPYGFTRVMSSYRWA
RNFVNGQDVNDWIGPPNNNGVIKEVTINADTTCGNDWVCEHRWRQIRNMVWFRNVVDGQP
FANWWANGSNQVAFGRGNRGFIVFNNDDWQLSSTLQTGLPGGTYCDVISGDKVGNSCTGI
KVYVSSDGTAQFSISNSAEDPFIAIHAESKL
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| BDBM50274062 |
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| n/a |
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| Name | BDBM50274062 |
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| Synonyms: | CHEMBL491789 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H28O4 |
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| Mol. Mass. | 356.4553 |
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| SMILES | COc1cccc(O)c1C(=O)CCCCCCCCc1ccc(O)cc1 |
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| Structure | 
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