| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Casein kinase I isoform epsilon |
|---|
| Ligand | BDBM50274761 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1714299 (CHEMBL4124348) |
|---|
| IC50 | >10000±n/a nM |
|---|
| Citation |  Dao, VH; Ourliac-Garnier, I; Bazin, MA; Jacquot, C; Baratte, B; Ruchaud, S; Bach, S; Grovel, O; Le Pape, P; Marchand, P Benzofuro[3,2-d]pyrimidines inspired from cercosporamide CaPkc1 inhibitor: Synthesis and evaluation of fluconazole susceptibility restoration. Bioorg Med Chem Lett28:2250-2255 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Casein kinase I isoform epsilon |
|---|
| Name: | Casein kinase I isoform epsilon |
|---|
| Synonyms: | n/a |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 47361.22 |
|---|
| Organism: | Sus scrofa |
|---|
| Description: | ChEMBL_117774 |
|---|
| Residue: | 416 |
|---|
| Sequence: | MELRVGNKYRLGRKIGSGSFGDIYLGANIASGEEVAIKLECVKTKHPQLHIESKFYKMMQ
GGVGIPSIKWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
CKGYPSEFSTYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGAARN
PEDVDRERREHEREERMGQLRGSATRALPPGPPTGATANRLRSAAEPVASTPASRLQQAG
NTSPRAISRVDRERKVSMRLHRGAPANVSSSDLTGRQEVSRISASQTSVPFDHLGK
|
|
|
|---|
| BDBM50274761 |
|---|
| n/a |
|---|
| Name | BDBM50274761 |
|---|
| Synonyms: | CHEMBL4127885 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H8N4O4 |
|---|
| Mol. Mass. | 260.2056 |
|---|
| SMILES | NC(=O)c1c(O)cc(O)c2c1oc1c(N)ncnc21 |
|---|
| Structure | 
|
|---|
Search and Browse
