| Reaction Details |
|---|
 | Report a problem with these data |
| Target | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
|---|
| Ligand | BDBM50276140 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1715364 (CHEMBL4125413) |
|---|
| IC50 | >200000±n/a nM |
|---|
| Citation |  Wang, C; Wang, F; Chen, X; Zou, Y; Zhu, H; Zhao, Q; Shen, J; Li, Y; Li, Y; He, B The mimics of N Bioorg Med Chem Lett28:2375-2378 (2018) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
|---|
| Name: | NAD-dependent protein deacetylase sirtuin-3, mitochondrial |
|---|
| Synonyms: | NAD-dependent deacetylase sirtuin 3 | NAD-dependent protein deacetylase sirtuin-3 (SIRT3) | SIR2L3 | SIR3_HUMAN | SIRT3 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 43582.69 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q9NTG7 |
|---|
| Residue: | 399 |
|---|
| Sequence: | MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEP
LDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDK
GKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIF
ELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIP
ASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQ
RFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDV
AQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK
|
|
|
|---|
| BDBM50276140 |
|---|
| n/a |
|---|
| Name | BDBM50276140 |
|---|
| Synonyms: | CHEMBL4129995 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C34H51N3O3S |
|---|
| Mol. Mass. | 581.852 |
|---|
| SMILES | CCCCCCCCCCCCCC(=S)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
