| Reaction Details |
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 | Report a problem with these data |
| Target | Squalene monooxygenase |
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| Ligand | BDBM50015508 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_201924 |
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| IC50 | 40000±n/a nM |
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| Citation |  Sen, SE; Wawrzenczyk, C; Prestwich, GD Inhibition of vertebrate squalene epoxidase by extended and truncated analogues of trisnorsqualene alcohol. J Med Chem33:1698-701 (1990) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Squalene monooxygenase |
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| Name: | Squalene monooxygenase |
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| Synonyms: | ERG1 | ERG1_HUMAN | SE | SQLE | Squalene epoxidase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63936.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_201924 |
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| Residue: | 574 |
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| Sequence: | MWTFLGIATFTYFYKKFGDFITLANREVLLCVLVFLSLGLVLSYRCRHRNGGLLGRQQSG
SQFALFSDILSGLPFIGFFWAKSPPESENKEQLEARRRRKGTNISETSLIGTAACTSTSS
QNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYHVLKDLGL
GDTVEGLDAQVVNGYMIHDQESKSEVQIPYPLSENNQVQSGRAFHHGRFIMSLRKAAMAE
PNAKFIEGVVLQLLEEDDVVMGVQYKDKETGDIKELHAPLTVVADGLFSKFRKSLVSNKV
SVSSHFVGFLMKNAPQFKANHAELILANPSPVLIYQISSSETRVLVDIRGEMPRNLREYM
VEKIYPQIPDHLKEPFLEATDNSHLRSMPASFLPPSSVKKRGVLLLGDAYNMRHPLTGGG
MTVAFKDIKLWRKLLKGIPDLYDDAAIFEAKKSFYWARKTSHSFVVNILAQALYELFSAT
DDSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLVLIGHFFAVAIYAVYFCFKSEPW
ITKPRALLSSGAVLYKACSVIFPLIYSEMKYMVH
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| BDBM50015508 |
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| n/a |
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| Name | BDBM50015508 |
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| Synonyms: | 3,7,12,16,20-Pentamethyl-henicosa-3,7,11,15,19-pentaen-1-ol | CHEMBL47577 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H44O |
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| Mol. Mass. | 372.627 |
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| SMILES | [#6]\[#6](-[#6])=[#6]/[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]\[#6]=[#6](/[#6])-[#6]-[#6]-[#8] |
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| Structure | 
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