| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma intracellular receptor 2 |
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| Ligand | BDBM50219754 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_1733120 |
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| Ki | 13±n/a nM |
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| Citation |  Sun, YT; Wang, GF; Yang, YQ; Jin, F; Wang, Y; Xie, XY; Mach, RH; Huang, YS Synthesis and pharmacological evaluation of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives as sigma-2 receptor ligands. Eur J Med Chem147:227-237 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma intracellular receptor 2 |
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| Name: | Sigma intracellular receptor 2 |
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| Synonyms: | MAC30 | Meningioma-associated protein 30 | S2R | SGMR2_HUMAN | Sigma-2 receptor | Sigma2 receptor | TMEM97 | Transmembrane protein 97 |
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| Type: | Protein |
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| Mol. Mass.: | 20857.20 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q5BJF2 |
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| Residue: | 176 |
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| Sequence: | MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQ
EPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLF
EDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK
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| BDBM50219754 |
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| n/a |
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| Name | BDBM50219754 |
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| Synonyms: | 1-cyclohexyl-4-[3-(9H-carbazol-9-yl)propyl]piperazine hydrochloride | CHEMBL536305 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H33N3 |
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| Mol. Mass. | 375.5496 |
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| SMILES | C(CN1CCN(CC1)C1CCCCC1)Cn1c2ccccc2c2ccccc12 |
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| Structure | 
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