| Reaction Details |
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 | Report a problem with these data |
| Target | Monoacylglycerol lipase ABHD6 |
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| Ligand | BDBM50408224 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1739439 (CHEMBL4155189) |
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| IC50 | >10000±n/a nM |
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| Citation |  Chicca, A; Arena, C; Bertini, S; Gado, F; Ciaglia, E; Abate, M; Digiacomo, M; Lapillo, M; Poli, G; Bifulco, M; Macchia, M; Tuccinardi, T; Gertsch, J; Manera, C Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system. Eur J Med Chem154:155-171 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Monoacylglycerol lipase ABHD6 |
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| Name: | Monoacylglycerol lipase ABHD6 |
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| Synonyms: | 2-arachidonoylglycerol hydrolase | ABHD6 | ABHD6_HUMAN | Abhydrolase domain-containing protein 6 | Monoacylglycerol lipase ABHD6 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 38341.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_105457 |
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| Residue: | 337 |
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| Sequence: | MDLDVVNMFVIAGGTLAIPILAFVASFLLWPSALIRIYYWYWRRTLGMQVRYVHHEDYQF
CYSFRGRPGHKPSILMLHGFSAHKDMWLSVVKFLPKNLHLVCVDMPGHEGTTRSSLDDLS
IDGQVKRIHQFVECLKLNKKPFHLVGTSMGGQVAGVYAAYYPSDVSSLCLVCPAGLQYST
DNQFVQRLKELQGSAAVEKIPLIPSTPEEMSEMLQLCSYVRFKVPQQILQGLVDVRIPHN
NFYRKLFLEIVSEKSRYSLHQNMDKIKVPTQIIWGKQDQVLDVSGADMLAKSIANCQVEL
LENCGHSVVMERPRKTAKLIIDFLASVHNTDNNKKLD
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| BDBM50408224 |
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| n/a |
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| Name | BDBM50408224 |
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| Synonyms: | CHEMBL4164954 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24BrFN2O2 |
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| Mol. Mass. | 435.33 |
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| SMILES | Cc1c(Br)cn(Cc2ccc(F)cc2)c(=O)c1C(=O)NC1CCCCCC1 |
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| Structure | 
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