| Reaction Details |
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 | Report a problem with these data |
| Target | Trypsin-3 |
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| Ligand | BDBM50449682 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1740413 (CHEMBL4156163) |
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| Ki | 335±n/a nM |
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| Citation |  de Veer, SJ; Li, CY; Swedberg, JE; Schroeder, CI; Craik, DJ Engineering potent mesotrypsin inhibitors based on the plant-derived cyclic peptide, sunflower trypsin inhibitor-1. Eur J Med Chem155:695-704 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Trypsin-3 |
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| Name: | Trypsin-3 |
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| Synonyms: | Brain trypsinogen | Mesotrypsinogen | PRSS3 | PRSS4 | Serine protease 3 | Serine protease 4 | TRY3 | TRY3_HUMAN | TRY4 | Thrombin & trypsin | Trypsin | Trypsin III | Trypsin IV | Trypsin-3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32532.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_216043 |
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| Residue: | 304 |
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| Sequence: | MCGPDDRCPARWPGPGRAVKCGKGLAAARPGRVERGGAQRGGAGLELHPLLGGRTWRAAR
DADGCEALGTVAVPFDDDDKIVGGYTCEENSLPYQVSLNSGSHFCGGSLISEQWVVSAAH
CYKTRIQVRLGEHNIKVLEGNEQFINAAKIIRHPKYNRDTLDNDIMLIKLSSPAVINARV
STISLPTTPPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSM
FCVGFLEGGKDSCQRDSGGPVVCNGQLQGVVSWGHGCAWKNRPGVYTKVYNYVDWIKDTI
AANS
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| BDBM50449682 |
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| n/a |
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| Name | BDBM50449682 |
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| Synonyms: | CHEMBL4176209 |
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| Type | Small organic molecule |
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| Emp. Form. | C64H98N18O19S2 |
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| Mol. Mass. | 1487.702 |
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| SMILES | CC[C@H](C)[C@@H]1NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@@H]2CSSC[C@H](NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N2)[C@@H](C)O |r| |
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| Structure | 
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