| Reaction Details |
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 | Report a problem with these data |
| Target | Capsid protein |
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| Ligand | BDBM50247735 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1743345 (CHEMBL4177855) |
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| EC50 | 35±n/a nM |
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| Citation |  Ren, Q; Liu, X; Luo, Z; Li, J; Wang, C; Goldmann, S; Zhang, J; Zhang, Y Discovery of hepatitis B virus capsid assembly inhibitors leading to a heteroaryldihydropyrimidine based clinical candidate (GLS4). Bioorg Med Chem25:1042-1056 (2017) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Capsid protein |
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| Name: | Capsid protein |
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| Synonyms: | Core antigen |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26278.39 |
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| Organism: | Hepatitis B virus |
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| Description: | ChEMBL_450484 |
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| Residue: | 230 |
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| Sequence: | MIFVLGGCRHKLVCSPAPCNFFHLCLIISCSCPTVHASKLCLGWLWGMHIDPYKEFGASV
ELLSFLPSDFFPSIRDLLDTASALYREALESPEHCSPHHTALRQAILCWGELMNLATWVG
SNLEDPASRELVVSYVNVNMGLKIRQLLWFHISCLTFGRETVLEYLVSFGVWIRTPPAYR
PPNAPILSTLPETTVVRRRGRSPRRRTPSPRRRRSQSPRRRRSQSRESQC
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| BDBM50247735 |
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| n/a |
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| Name | BDBM50247735 |
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| Synonyms: | CHEMBL4075908 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21BrFN5O3S |
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| Mol. Mass. | 510.38 |
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| SMILES | CCOC(=O)C1=C(CN2CCOCC2)NC(=NC1c1ccc(F)cc1Br)c1nncs1 |c:5,16| |
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| Structure | 
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