| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosinase |
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| Ligand | BDBM50031467 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1748808 (CHEMBL4183318) |
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| IC50 | 52000±n/a nM |
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| Citation |  Ferro, S; Deri, B; Germanò, MP; Gitto, R; Ielo, L; Buemi, MR; Certo, G; Vittorio, S; Rapisarda, A; Pazy, Y; Fishman, A; De Luca, L Targeting Tyrosinase: Development and Structural Insights of Novel Inhibitors Bearing Arylpiperidine and Arylpiperazine Fragments. J Med Chem61:3908-3917 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosinase |
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| Name: | Tyrosinase |
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| Synonyms: | Tyrosinase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 34417.83 |
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| Organism: | Bacillus megaterium |
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| Description: | ChEMBL_117879 |
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| Residue: | 297 |
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| Sequence: | MSNKYRVRKNVLHLTDTEKRDFVRTVLILKEKGIYDRYIAWHGAAGKFHTPPGSDRNAAH
MSSAFLPWHREYLLRFERDLQSINPEVTLPYWEWETDAQMQDPSQSQIWSADFMGGNGNP
IKDFIVDTGPFAAGRWTTIDEQGNPSGGLKRNFGATKEAPTLPTRDDVLNALKITQYDTP
PWDMTSQNSFRNQLEGFINGPQLHNRVHRWVGGQMGVVPTAPNDPVFFLHHANVDRIWAV
WQIIHRNQNYQPMKNGPFGQNFRDPMYPWNTTPEDVMNHRKLGYVYDIELRKSKRSS
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| BDBM50031467 |
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| n/a |
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| Name | BDBM50031467 |
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| Synonyms: | 5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hydroxy-2-hydroxymethyl-pyran-4-one | CHEMBL287556 | Kojic Acid | US10857082, Kojic acid | US9422261, Kojic acid | US9682910, kojic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C6H6O4 |
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| Mol. Mass. | 142.1094 |
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| SMILES | OCc1cc(=O)c(O)co1 |
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| Structure | 
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