| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 6 |
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| Ligand | BDBM50454291 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1752577 (CHEMBL4187337) |
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| Kd | 58800±n/a nM |
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| Citation |  ?apkauskait?, E; Zak?auskas, A; Ruibys, V; Linkuvien?, V; Paketuryt?, V; Gedgaudas, M; Kairys, V; Matulis, D Benzimidazole design, synthesis, and docking to build selective carbonic anhydrase VA inhibitors. Bioorg Med Chem26:675-687 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 6 |
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| Name: | Carbonic anhydrase 6 |
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| Synonyms: | CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase |
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| Type: | Enzyme |
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| Mol. Mass.: | 35371.40 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P23280 |
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| Residue: | 308 |
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| Sequence: | MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYN
PSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSE
ISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNF
ISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLS
RTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEIL
DYLRRALN
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| BDBM50454291 |
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| n/a |
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| Name | BDBM50454291 |
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| Synonyms: | CHEMBL4207242 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H20ClN3O3S2 |
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| Mol. Mass. | 486.006 |
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| SMILES | Cc1cc2ncn(CC(=O)c3cc(c(Cl)cc3Sc3ccccc3)S(N)(=O)=O)c2cc1C |
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| Structure | 
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