| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glycine receptor subunit alpha-3 |
|---|
| Ligand | BDBM50229711 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1767509 (CHEMBL4219621) |
|---|
| EC50 | 454±n/a nM |
|---|
| Citation |  Sparling, BA; DiMauro, EF Progress in the discovery of small molecule modulators of the Cys-loop superfamily receptors. Bioorg Med Chem Lett27:3207-3218 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Glycine receptor subunit alpha-3 |
|---|
| Name: | Glycine receptor subunit alpha-3 |
|---|
| Synonyms: | GLRA3 | GLRA3_HUMAN | Glycine receptor alpha-3/beta |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 53809.29 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_967474 |
|---|
| Residue: | 464 |
|---|
| Sequence: | MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDAR
IRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDP
SMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPM
DVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKF
TCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQS
SGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEA
FALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKV
FIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD
|
|
|
|---|
| BDBM50229711 |
|---|
| n/a |
|---|
| Name | BDBM50229711 |
|---|
| Synonyms: | CHEMBL4074873 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H17N3O4S |
|---|
| Mol. Mass. | 383.421 |
|---|
| SMILES | [H][C@@]12CN(C[C@]1([H])c1cnccc1N(C)C2=O)S(=O)(=O)c1ccc2occc2c1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
