| Reaction Details |
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 | Report a problem with these data |
| Target | C3a anaphylatoxin chemotactic receptor |
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| Ligand | BDBM50462095 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1772738 (CHEMBL4229730) |
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| IC50 | 50±n/a nM |
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| Citation |  Iyer, A; Xu, W; Reid, RC; Fairlie, DP Chemical Approaches to Modulating Complement-Mediated Diseases. J Med Chem61:3253-3276 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C3a anaphylatoxin chemotactic receptor |
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| Name: | C3a anaphylatoxin chemotactic receptor |
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| Synonyms: | AZ3B | C3AR | C3AR1 | C3AR_HUMAN | C3R1 | C3a-R | HNFAG09 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53864.66 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_642034 |
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| Residue: | 482 |
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| Sequence: | MASFSAETNSTDLLSQPWNEPPVILSMVILSLTFLLGLPGNGLVLWVAGLKMQRTVNTIW
FLHLTLADLLCCLSLPFSLAHLALQGQWPYGRFLCKLIPSIIVLNMFASVFLLTAISLDR
CLVVFKPIWCQNHRNVGMACSICGCIWVVAFVMCIPVFVYREIFTTDNHNRCGYKFGLSS
SLDYPDFYGDPLENRSLENIVQPPGEMNDRLDPSSFQTNDHPWTVPTVFQPQTFQRPSAD
SLPRGSARLTSQNLYSNVFKPADVVSPKIPSGFPIEDHETSPLDNSDAFLSTHLKLFPSA
SSNSFYESELPQGFQDYYNLGQFTDDDQVPTPLVAITITRLVVGFLLPSVIMIACYSFIV
FRMQRGRFAKSQSKTFRVAVVVVAVFLVCWTPYHIFGVLSLLTDPETPLGKTLMSWDHVC
IALASANSCFNPFLYALLGKDFRKKARQSIQGILEAAFSEELTRSTHCPSNNVISERNST
TV
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| BDBM50462095 |
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| n/a |
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| Name | BDBM50462095 |
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| Synonyms: | CHEMBL4239466 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22BrN5O4 |
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| Mol. Mass. | 464.313 |
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| SMILES | NC(=N)NCCC[C@H](NC(=O)c1cccn(Cc2ccccc2Br)c1=O)C(O)=O |r| |
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| Structure | 
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