| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteine proteinase falcipain 2a |
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| Ligand | BDBM50463154 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1777774 (CHEMBL4234766) |
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| IC50 | 60±n/a nM |
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| Citation |  Royo, S; Schirmeister, T; Kaiser, M; Jung, S; Rodríguez, S; Bautista, JM; González, FV Antiprotozoal and cysteine proteases inhibitory activity of dipeptidyl enoates. Bioorg Med Chem26:4624-4634 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cysteine proteinase falcipain 2a |
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| Name: | Cysteine proteinase falcipain 2a |
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| Synonyms: | Cysteine protease falcipain-2 |
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| Type: | Protein |
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| Mol. Mass.: | 55996.21 |
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| Organism: | Plasmodium falciparum |
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| Description: | Q9NBD4 |
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| Residue: | 484 |
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| Sequence: | MDYNMDYAPHEVISHQGERFVDKYVDRKILKNKKSLLVIISLSVLSVVGFILFYFTPNFR
KSDLFKNSSVENNNDDYIINSLLKSPNGKKFIVSKIDEALSFYDSKKNDINKYNEGNNNN
NADFKGLSLFKENTPSNNFIHNKDYFINFFDNKFLMNNAEHINQFYMFIKTNNKQYNSPN
EMKERFQVFLQNAHKVNMHNNNKNSLYKKELNRFADLTYHEFKNKYLSLRSSKPLKNSKY
LLDQMNYEEVIKKYRGEENFDHAAYDWRLHSGVTPVKDQKNCGSCWAFSSIGSVESQYAI
RKNKLITLSEQELVDCSFKNYGCNGGLINNAFEDMIELGGICPDGDYPYVSDAPNLCNID
RCTEKYGIKNYLSVPDNKLKEALRFLGPISISVAVSDDFAFYKEGIFDGECGDELNHAVM
LVGFGMKEIVNPLTKKGEKHYYYIIKNSWGQQWGERGFINIETDESGLMRKCGLGTDAFI
PLIE
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| BDBM50463154 |
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| n/a |
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| Name | BDBM50463154 |
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| Synonyms: | CHEMBL4251480 |
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| Type | Small organic molecule |
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| Emp. Form. | C32H34N2O6 |
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| Mol. Mass. | 542.6222 |
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| SMILES | CCOC(=O)\C=C\C(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 |r| |
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| Structure | 
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