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TargetMitochondrial pyruvate carrier 2
LigandBDBM228129
Substrate/Competitorn/a
Meas. Tech.ChEMBL_1793755 (CHEMBL4265674)
IC50 1200±n/a nM
Citation Tanis, SPColca, JRParker, TTArtman, GDLarsen, SDMcDonald, WGGadwood, RCKletzien, RFZeller, JBLee, PHAdams, WJ PPAR?-sparing thiazolidinediones as insulin sensitizers. Design, synthesis and selection of compounds for clinical development. Bioorg Med Chem26:5870-5884 (2018) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mitochondrial pyruvate carrier 2
Name:Mitochondrial pyruvate carrier 2
Synonyms:BRP44 | Brain protein 44 | MPC2 | MPC2_HUMAN | Mitochondrial pyruvate carrier 2
Type:PROTEIN
Mol. Mass.:14291.32
Organism:Homo sapiens
Description:ChEMBL_117931
Residue:127
Sequence:
MSAAGARGLRATYHRLLDKVELMLPEKLRPLYNHPAGPRTVFFWAPIMKWGLVCAGLADM
ARPAEKLSTAQSAVLMATGFIWSRYSLVIIPKNWSLFAVNFFVGAAGASQLFRIWRYNQE
LKAKAHK
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  Blast E-value cutoff:
BDBM228129
n/a
NameBDBM228129
Synonyms:US9562012, mitoglitazone
TypeSmall organic molecule
Emp. Form.C19H18N2O4S
Mol. Mass.370.422
SMILESCCc1ccc(nc1)C(=O)COc1ccc(CC2SC(=O)NC2=O)cc1
Structure
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