| Reaction Details |
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 | Report a problem with these data |
| Target | Type-1 angiotensin II receptor |
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| Ligand | BDBM50047875 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_901575 (CHEMBL3068556) |
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| IC50 | 6.8±n/a nM |
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| Citation |  TBA Med Chem Res21:2307-2315 (2012) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-1 angiotensin II receptor |
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| Name: | Type-1 angiotensin II receptor |
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| Synonyms: | AGTR1 | AGTR1_RABIT | ANGIOTENSIN AT1 | Angiotensin II receptor | Angiotensin II type 1a (AT-1a) receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41009.15 |
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| Organism: | RABBIT |
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| Description: | ANGIOTENSIN AT1 AGTR1 RABBIT::P34976 |
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| Residue: | 359 |
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| Sequence: | MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLK
TVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLT
CLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVC
AFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFK
IIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPL
FYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
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| BDBM50047875 |
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| n/a |
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| Name | BDBM50047875 |
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| Synonyms: | CHEMBL347135 | N-{4-[3-Butyl-5-(4-chloro-benzylsulfanyl)-[1,2,4]triazol-4-ylmethyl]-phenyl}-phthalamic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C28H27ClN4O3S |
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| Mol. Mass. | 535.057 |
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| SMILES | CCCCc1nnc(SCc2ccc(Cl)cc2)n1Cc1ccc(NC(=O)c2ccccc2C(O)=O)cc1 |
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| Structure | 
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