| Reaction Details |
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 | Report a problem with these data |
| Target | Trophozoite cysteine proteinase |
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| Ligand | BDBM50486876 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_903031 (CHEMBL3063284) |
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| IC50 | 710±n/a nM |
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| Citation |  TBA Med Chem Res21:3835-3847 (2012) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Trophozoite cysteine proteinase |
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| Name: | Trophozoite cysteine proteinase |
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| Synonyms: | 3.4.22.- | CYSP_PLAFA | TCP | Trophozoite cysteine proteinase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66893.11 |
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| Organism: | Plasmodium falciparum |
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| Description: | ChEMBL_106615 |
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| Residue: | 569 |
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| Sequence: | MVAIKEMKELAFARPSLVETLNKKKKFLKKKEKRTFVLSIYAFITFIIFCIGILYFTNKS
SAHNNNNNKNEHSLKKEEIELLRVLLEKYKKQKDGILNESSNEEDEEKYTLNSETYNNKN
NVSNIKNDSIKSKKEEYINLERILLEKYKKFINENNEENRKELSNILHKLLEINKLILRE
EKDDKKVYLINDNYDEKGALEIGMNEEMKYKKEDPINNIKYASKFFKFMKEHNKVYKNID
EQMRKFEIFKINYISIKNHNKLNKNAMYKKKVNQFSDYSEEELKEYFKTLLHVPNHMIEK
YSKPFENHLKDNILISEFYTNGKRNEKDIFSKVPEILDYREKGIVHEPKDQGLCGSCWAF
ASVGNIESVFAKKNKNILSFSEQEVVDCSKDNFGCDGGHPFYSFLYVLQNELCLGDEYKY
KAKDDMFCLNYRCKRKVSLSSIGAVKENQLILALNEVGPLSVNVGVNNDFVAYSEGVYNG
TCSEELNHSVLLVGYGQVEKTKLNYNNKIQTYNTKENSNQPDDNIIYYWIIKNSWSKKWG
ENGFMRLSRNKNGDNVFCGIGEEVFYPIL
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| BDBM50486876 |
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| n/a |
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| Name | BDBM50486876 |
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| Synonyms: | CHEMBL2237689 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H11ClN2O |
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| Mol. Mass. | 294.735 |
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| SMILES | Clc1nc2ccccc2cc1C(=O)\C=C\c1cccnc1 |
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| Structure | 
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