| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin S |
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| Ligand | BDBM50032803 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_48683 (CHEMBL658353) |
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| Ki | 5.9±n/a nM |
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| Citation |  Palmer, JT; Rasnick, D; Klaus, JL; Brömme, D Vinyl sulfones as mechanism-based cysteine protease inhibitors. J Med Chem38:3193-6 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin S |
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| Name: | Cathepsin S |
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| Synonyms: | CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein |
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| Type: | Protein |
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| Mol. Mass.: | 37507.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25774 |
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| Residue: | 331 |
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| Sequence: | MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
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| BDBM50032803 |
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| n/a |
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| Name | BDBM50032803 |
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| Synonyms: | 2-((E)-2-Benzenesulfonyl-vinylamino)-N-[3-methyl-1-(3-morpholin-4-yl-ureidocarbonyl)-butyl]-4-phenyl-butyramide | CHEMBL108746 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H39N5O6S |
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| Mol. Mass. | 585.715 |
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| SMILES | CC(C)CC(NC(=O)C(CCc1ccccc1)N=CCS(=O)(=O)c1ccccc1)C(=O)NC(=O)NN1CCOCC1 |w:17.17| |
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| Structure | 
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