| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Target of rapamycin complex subunit LST8 |
|---|
| Ligand | BDBM50490556 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_947375 (CHEMBL2344608) |
|---|
| IC50 | 1.000000±n/a nM |
|---|
| Citation |  Abdel-Magid, AF Inhibition of mTOR Kinase and Cancer Treatment. ACS Med Chem Lett4:321-2 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Target of rapamycin complex subunit LST8 |
|---|
| Name: | Target of rapamycin complex subunit LST8 |
|---|
| Synonyms: | G protein beta subunit-like | GBL | Gable | LST8 | LST8_HUMAN | MLST8 | Mammalian lethal with SEC13 protein 8 | Protein GbetaL | TORC subunit LST8 | Target of rapamycin complex subunit LST8 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 35871.25 |
|---|
| Organism: | Homo sapiens |
|---|
| Description: | ChEMBL_118692 |
|---|
| Residue: | 326 |
|---|
| Sequence: | MNTSPGTVGSDPVILATAGYDHTVRFWQAHSGICTRTVQHQDSQVNALEVTPDRSMIAAA
GYQHIRMYDLNSNNPNPIISYDGVNKNIASVGFHEDGRWMYTGGEDCTARIWDLRSRNLQ
CQRIFQVNAPINCVCLHPNQAELIVGDQSGAIHIWDLKTDHNEQLIPEPEVSITSAHIDP
DASYMAAVNSTGNCYVWNLTGGIGDEVTQLIPKTKIPAHTRYALQCRFSPDSTLLATCSA
DQTCKIWRTSNFSLMTELSIKSGNPGESSRGWMWGCAFSGDSQYIVTASSDNLARLWCVE
TGEIKREYGGHQKAVVCLAFNDSVLG
|
|
|
|---|
| BDBM50490556 |
|---|
| n/a |
|---|
| Name | BDBM50490556 |
|---|
| Synonyms: | CHEMBL2338394 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H23N11O |
|---|
| Mol. Mass. | 505.5339 |
|---|
| SMILES | [H][C@]12CC[C@]([H])(C[C@H](C1)c1nc3c(cnn3c3[nH]ccc13)-c1ccc(nc1)-c1ncc[nH]1)N2C(=O)c1nnc[nH]1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
