| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
|---|
| Ligand | BDBM50493351 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_981006 (CHEMBL2427727) |
|---|
| Ki | 3631±n/a nM |
|---|
| Citation |  Párraga, J; Cabedo, N; Andujar, S; Piqueras, L; Moreno, L; Galán, A; Angelina, E; Enriz, RD; Ivorra, MD; Sanz, MJ; Cortes, D 2,3,9- and 2,3,11-trisubstituted tetrahydroprotoberberines as D2 dopaminergic ligands. Eur J Med Chem68:150-66 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(1A) dopamine receptor |
|---|
| Name: | D(1A) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 49429.75 |
|---|
| Organism: | RAT |
|---|
| Description: | P18901 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
|
|
|
|---|
| BDBM50493351 |
|---|
| n/a |
|---|
| Name | BDBM50493351 |
|---|
| Synonyms: | CHEMBL2425374 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H23NO3 |
|---|
| Mol. Mass. | 325.4015 |
|---|
| SMILES | COc1cccc2CC3N(CCc4cc(OC)c(OC)cc34)Cc12 |
|---|
| Structure | 
|
|---|
Search and Browse
