| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50040049 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29109 (CHEMBL638721) |
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| Ki | 14000±n/a nM |
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| Citation |  Franchetti, P; Messini, L; Cappellacci, L; Grifantini, M; Lucacchini, A; Martini, C; Senatore, G 8-Azaxanthine derivatives as antagonists of adenosine receptors. J Med Chem37:2970-5 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_BOVIN | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | ADORA1 | Adenosine A1 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 36602.99 |
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| Organism: | BOVINE |
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| Description: | ADENOSINE 0 BOVINE::P28190 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
PRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPVDEDAPAERPDD
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| BDBM50040049 |
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| n/a |
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| Name | BDBM50040049 |
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| Synonyms: | 1-(2-Amino-4-chloro-phenyl)-4,6-dimethyl-1,4-dihydro-[1,2,3]triazolo[4,5-d]pyrimidine-5,7-dione | CHEMBL328812 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H11ClN6O2 |
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| Mol. Mass. | 306.708 |
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| SMILES | Cn1c2nnn(-c3ccc(Cl)cc3N)c2c(=O)n(C)c1=O |
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| Structure | 
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